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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25263702171a90a3f892b57297f94483532fc8a36d6700e0a848670329ed5daa' 
  AND token = 'pTFudsSFF9LIlVoVECXmSZs6z66N+pFNzr+HdD/I5Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}