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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c51b5a88cfabbaa4b3f11e7f7a2834b22a71c2be420038480b08fac1e24ee8' 
  AND token = 'X9tXDylZ/PFM9Ec6424WWRbFTGbiEL3H3o7gdwhpTis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}