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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc588665916677b9ed8f292a29d0e2716d14b6b96c4d44d5aa21caa9c0a67bf0' 
  AND token = 'nRHO7S2gLTZZqLwwOdwGwWbiO+gQLKfXlR56qlOBHHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}