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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433ae2332b4b68fc59b6809647094041a00cf805368577bd47adce0bbbd0ca9a' 
  AND token = '+pnB07Am+kWDWpeqIU5qN0oqax/FAwY+wzC7GRVbaTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}