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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b53aa3c2928c245bb04bc04c44280013d274f04751ed137fdd7075d9df6cb59' 
  AND token = 'OM0FIEr9iwQ1x6KaBWmBzDM27E2P2qq3E1TrGW2/yk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}