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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e66d1ce5ad78103df8ae4c65bc7afe017671b193126b0fc63f6424989e1570' 
  AND token = 'wYlz7pg2mEbaMw0ru+eW2F4btH6iDVErjqFq1MkZ3zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}