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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9a13bbd61181a101e0541db644dd7e9f0ea1b6e607c2eae83251ae1083fc75' 
  AND token = 'dyWDQWtSzvqF+h//gedUuUxSEHbqoSB0ggg9mS9yefQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}