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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ebd1a727a801d50e873b62a76dfe73bb1cff545c67ee6f50df5c8636fbb191e' 
  AND token = 'j7ep956D9xfteTa12ObdvkCCTujIB0o2FozXsMBfWR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}