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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1bb12a42b8640c19d49fed1c50cb42847bb6a2ca60dca08e745395892950d52' 
  AND token = 'Q06PEaC6as2sTdhWAtCvrJvVi2PZr+rSCiwORg7Lbdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}