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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ee99f7b75469130743889effc9d31512789e728250003b348b66e762694a25' 
  AND token = 'q++YmMfkR/RpOrnkGrEaqe3Ia6QRk26qs5X7nBIP29Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}