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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '920125f453ee868ed492877b9a1fb98d158a03fd10d9381129984a90018c7d0d' 
  AND token = '+z+pQSt3SxZqFj9n7V2xl1x3N405OYHF27IPRkzRTBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}