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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9b8275dbe125084abc34139c15d0604d7ad5913d922f6fcde3c4d36b1110e0e' 
  AND token = 'hTNLsZdnsRLSZl+I13nk8zV8EkAZ5fnY8/R0IiRjjEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}