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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '509294e2690d72a693e814348562490ef6fb17f8059313263ad63ec616b0c0bf' 
  AND token = 'Q+HOEDQqTgYXp1Gd717QdCF4BYUE11efEvKT7wlfgkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}