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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb046e8c5b396f7e31c1e43b9c1f710b1e15ace87a8197524dd970d64ea71f8d' 
  AND token = 'hjt6qxxHcYGcwEfEyzaMOTq+gcA1uLPEz3eMSJUTyNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}