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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2c77746e6407ec1f85e479a7ae33bf4ad85efa2f32a294482d6ee458d9d2fb' 
  AND token = 'jaE5fUrqoDBePHikzdqZqw4aiUjrroR/aTlVRi7Ju8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}