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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b38ef32b3a5cecbdb2fc0711f691ce873cbce2671760eb8b7ac16340da4152' 
  AND token = '+wdKlmxImj/xX4sbpTwGzEaGwIleyCP8j2rkB4M8iQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}