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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b81e0762ff68cec171b00e6328b8072185dec26c36208e68a1f9d7a11d1e21' 
  AND token = 'nM+u73qWHwlq9iiV1iVFaaaJwFkxIfIk1503DKdEuLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}