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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e59013bdf17e78dbb1509959c7fb00a2966bcde0eea3fdf385d83bd9fe252d8' 
  AND token = '3YRtPpHfA7MAEkg0mJWViVcun7hPx/1P5/L86Sbq14E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}