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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2412e229dc3700cd6fb4ff8c54f2351a741ad945b8268c33c71cd3887fed7b' 
  AND token = 'ZYBbmWbRndeQLdb1ix8CZG7VOPfD79l3laijfX1bUWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}