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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ee849a407bcbf8c27e5774b1aea5b9f357cbd3cae859a60faffebb23dd15e8c' 
  AND token = 'x2+Ho8H+jNAaBAQFAl84x+gfhIaZ4+QQL4k44GZAyq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}