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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de7d0174771a9f84fe3ead0643eb157f2aa1ede531e0e6e1e5a3f781d25b7e6' 
  AND token = 'I8MzovCa1nR+ilW2Ra0ccZ0KMXSxtl191fDENHvHQaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}