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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd5b4e02f8147f9f3664e3dd1fc1138505de00c74fff50f2158eec510650ef2' 
  AND token = 'D7+pxlV6+r9tS2dUM5oPOX1nQ1UxRgjW2NnsP9ZdJlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}