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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c77a36162e641b57e830c57720abd66c826e209ac191bcb30745e1696f482c97' 
  AND token = 'DhXEVUgX29jnfTEM0ikWrfc6wCai3zLMVVrMqQXG9hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}