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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a4a1c2c622cef34ba37d1b730bb629368052a96877acf3ab0579d0ea01951f7' 
  AND token = 'ANYmpOFvqPOTZCjRBaAuDQxT7JdE9xsSt+DiU9pLeEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}