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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b3a99aa1c1d0ae731176eb18b59619e727721ea37b7f4a2951c27b3187be94' 
  AND token = 'gjJyZmKW6y3Me11Mpu8bpp8QlrdVuUwBPdMjFnHEUbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}