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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe28228384399d274ea98e83bf42d2d0ea5062a0ae0f54497a6d351a5b25f20' 
  AND token = 'Z897K9nBDhAk8e7Xyt3qTNEUKr3PmZYmP4q29TWXQZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}