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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f1e67b2ec41033f4f0e4f2e0eb6a112f8cb276364c20e3da6cdaf501e59d5a7' 
  AND token = 'O5O+lvh053WuQmX1kqZRPBsaiNSFmviwAFJtleU+Bjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}