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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c6a7b4c43a533c1c4b95bb4fcce9a88464520bb85af89ab64e96aa7bbc9750' 
  AND token = 'CKM7WfuaExlYYV7o+IwLQSOS9RauNc0pQZZQkCtZO/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}