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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6719940244ac946c17cf574b7012229a06cef8da3cfb5a7854d42f1f902663' 
  AND token = '/5o7R04t9pqgQREj1NmtCB74sJx0k8mWoyXD79bmo/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}