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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88baf72334ffb90e80aa06aecd63fb39c2b15cdd12ac538847de62d03727cd78' 
  AND token = 'PAhmUPt4BFUQxFXyBcGd2iKIELS7ZbiQr3nrwRIM6E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}