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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1b2921fce37bab4f2dd42793bb2e18dd22189d50e48782cff1bcbf7fb8e1f0' 
  AND token = '8e3SJAzbD8Kkd8NC3PM1kJllNeH33FdCvN+oF8JeSBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}