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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d289ca05f734d2c81fb2944386403e378a6f007958758b1605e493b61d2f19d' 
  AND token = 'qdzeYL7nNjf1ixxY4RRXEpzxGED0X590V0g/IPbRj0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}