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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5f3975d91dab3f4253e45f02bcf553c1ac0cbe40a4e24f98c9d80727a446f7' 
  AND token = 'k3/IN82MmAUxcBGj2mV8kyEcpAE3Ck4ywbqc7sazUxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}