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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0271a4dfcf300d97b482f74cc7850ac542dc650fbeaf8cc39481fecd20de7a35' 
  AND token = 'nJm6yr1p86UPcQyh7G34m7dtkUI/Fn/AdmG5RXdt6mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}