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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469ea59236b1507de67507ebe5fb3cbb6a7ff9bab32a1ce36c61ca019e7b93aa' 
  AND token = 'nb/Lu3RuOn9FRxF0No5/GKInmOn+WrxJvJpq+Hetzn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}