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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249df1d0036028ead30ed648851d54ee4cab213ec9a4eb8b65a712fab0b277c2' 
  AND token = '0u5CaxrdVvA8mVKNV/DJ/eN8XsjmjzVOGIb72lmOUd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}