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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6294fa8bae42133babb04671dbe8505f1b8bbc0dad3d2c5365c9b12e04d6feac' 
  AND token = 'dmj+Zyo2Dl7R0e7d3X8tnoKWQViUXt0Qm07JYHFHDgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}