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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46051df857ade3aa1ac2ad8b17abcbd5e5c49c11310e7decf72073114e29c32b' 
  AND token = 'N/afQVo19aJhnfaOfKI/vQ6l8v+DzMHmFnKNrG6ZHw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}