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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dcb402d5b9bd8650782555c0d8856931bf6c8ec300389d89d3a6b016f09a1f5' 
  AND token = 'XNuP0NjfC1XAmF4e8dZQgI0feBrtjIxBB1mc1maaQ04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}