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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb89bb9ac7cb89cad8ec729cb1d6074d9c260df904e768dc9196cce479c5d49e' 
  AND token = 'XCOyTgkRxLfwTSvoh3bZhM3MS+2O1PYyguMVEfC2sdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}