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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3d248589e59d24021c64073d623cd6deac48be38024b2e761f5e150f00e100' 
  AND token = 'zP+XAwAI5GgZLa38fXpW1lHK3SoELp7m3HRggrkFiAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}