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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433e158cf00d43a44c8eafdf9ce99766a1658b4ea419cc42e0d49a4c3c25f5b0' 
  AND token = 'd0z0Gi/0mWFma+WEommUouwgl9jFv7ZGKdKoSwSZdoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}