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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105ce348ae1ba6c0c3392c8f52f39975df36c3d54a595ce126cf3b8ec3d647b6' 
  AND token = 'e6y3wDmxScq5KztuIaJE9xLcVJuefsNTkNT2XsDBh5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}