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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0cf5c0646874a024d7c1db72393c72204d7c36ced2adf6d2067b36eaee5c62' 
  AND token = 'NJ6M4RztUNW3YnIYikaAhCQBCOYotkh9/T0Cw94AUEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}