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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93b21fb83c3d094976a2e4cc11cc51dd13965e03715c15e3b0a43b4dee57a1d0' 
  AND token = '1bGe1JT4UuHl8wnOoDQN/uOui6VzP9sZnfKsiyoIdvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}