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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc7585a18451bbfb5090dec731e7a9c49c5bb8447c4e22b7b6f33a5af613816' 
  AND token = '23qHUzw4Kv4lMAAf/QKa7yAwfnVYLAMo7qn2qMu0zWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}