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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd5dbf6d182f836342e18cf211dd67d849d24619787cc8ee2caee5001c24279a' 
  AND token = '17lMC+ZPqcG2gvzFXwqMjuaU4QtvDVdE7+3j65zA75g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}