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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5faebb6aac5930859e072dd0799f9bb455e199d2018d9ed2d3da45502729294' 
  AND token = 'qFfaaDylEVAHdmCdMOIU4O7CpYryTrEIE+sCBVs1tpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}