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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb45d68940497ab210dc79d6b7e5fcd4b5d5b6a360bd960cf3dd14cb60f26a46' 
  AND token = 'MTMbgraIsrwB3U3kfPBbtVuvfkqNcYxlIkW5R2ZQits=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}