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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c616756058fccb29cc6fda6ee97fb8e13f944860e71d83fe765c88568407646' 
  AND token = 'E9MWsZRbFMKI3BbUJFYKnVp2OeRc2nRgNLHm7/9mSag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}